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Addgene: Lox-stop-Lox p53 R172H
Addgene: Lox-stop-Lox p53 R172H

Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome:  Cell
Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome: Cell

Comparison of Effects of p53 Null and Gain-of-Function Mutations on  Salivary Tumors in MMTV-Hras Transgenic Mice | PLOS ONE
Comparison of Effects of p53 Null and Gain-of-Function Mutations on Salivary Tumors in MMTV-Hras Transgenic Mice | PLOS ONE

Synergistic and additive effect of retinoic acid in circumventing  resistance to p53 restoration | PNAS
Synergistic and additive effect of retinoic acid in circumventing resistance to p53 restoration | PNAS

p53 transcripts in p53 +/+ and p53 R172H/R172H mice testes. (a) p53... |  Download Scientific Diagram
p53 transcripts in p53 +/+ and p53 R172H/R172H mice testes. (a) p53... | Download Scientific Diagram

p53_mouse
p53_mouse

Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in  Pancreatic Cancer - ScienceDirect
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer - ScienceDirect

Mutant p53 accumulates in cycling and proliferating cells in the normal  tissues of p53 R172H mutant mice. - Abstract - Europe PMC
Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice. - Abstract - Europe PMC

The hot-spot p53R172H mutant promotes formation of giant spermatogonia  triggered by DNA damage | Oncogene
The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage | Oncogene

The hot-spot p53R172H mutant promotes formation of giant spermatogonia  triggered by DNA damage | Oncogene
The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage | Oncogene

Gain-of-function p53R172H mutation drives accumulation of neutrophils in  pancreatic tumors, promoting resistance to immunotherapy - ScienceDirect
Gain-of-function p53R172H mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy - ScienceDirect

The hot-spot p53R172H mutant promotes formation of giant spermatogonia  triggered by DNA damage | Oncogene
The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage | Oncogene

Residual apoptotic activity of a tumorigenic p53 mutant improves cancer  therapy responses | The EMBO Journal
Residual apoptotic activity of a tumorigenic p53 mutant improves cancer therapy responses | The EMBO Journal

Mutant p53 expression in various spermatogonia and subset of Leydig... |  Download Scientific Diagram
Mutant p53 expression in various spermatogonia and subset of Leydig... | Download Scientific Diagram

GOF p53 interacts with Med17 and amino acid acids at mouse p53 L25, W26...  | Download Scientific Diagram
GOF p53 interacts with Med17 and amino acid acids at mouse p53 L25, W26... | Download Scientific Diagram

ZMC1 reactivates p53 R172H in BRCA1-deficient cell lines derived from... |  Download Scientific Diagram
ZMC1 reactivates p53 R172H in BRCA1-deficient cell lines derived from... | Download Scientific Diagram

Mutant p53 results in reduced survival, but phenotypically similar... |  Download Scientific Diagram
Mutant p53 results in reduced survival, but phenotypically similar... | Download Scientific Diagram

The generation of a mouse containing a p53R172H substitution. ( a ) The...  | Download Scientific Diagram
The generation of a mouse containing a p53R172H substitution. ( a ) The... | Download Scientific Diagram

The hot-spot p53R172H mutant promotes formation of giant spermatogonia  triggered by DNA damage | Oncogene
The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage | Oncogene

A Mouse Homolog of a Human TP53 Germline Mutation Reveals a Lipolytic  Activity of p53 - ScienceDirect
A Mouse Homolog of a Human TP53 Germline Mutation Reveals a Lipolytic Activity of p53 - ScienceDirect

Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome:  Cell
Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome: Cell

High metastatic potential in mice inheriting a targeted p53 missense  mutation | PNAS
High metastatic potential in mice inheriting a targeted p53 missense mutation | PNAS

Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome:  Cell
Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome: Cell

Mutant p53 accumulates in cycling and proliferating cells in the normal  tissues of p53 R172H mutant mice. - Abstract - Europe PMC
Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice. - Abstract - Europe PMC

Addgene: Lox-stop-Lox p53 R172H
Addgene: Lox-stop-Lox p53 R172H

The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment  of PLK3 | Nature Communications
The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3 | Nature Communications

Biomolecules | Free Full-Text | Advanced Strategies for Therapeutic  Targeting of Wild-Type and Mutant p53 in Cancer
Biomolecules | Free Full-Text | Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer

The p53R172H Mutant Does Not Enhance Hepatocellular Carcinoma Development  and Progression | PLOS ONE
The p53R172H Mutant Does Not Enhance Hepatocellular Carcinoma Development and Progression | PLOS ONE